powsimR: power analysis for bulk and single cell RNA-seq experiments

نویسندگان

  • Beate Vieth
  • Christoph Ziegenhain
  • Swati Parekh
  • Wolfgang Enard
  • Ines Hellmann
چکیده

Summary Power analysis is essential to optimize the design of RNA-seq experiments and to assess and compare the power to detect differentially expressed genes in RNA-seq data. PowsimR is a flexible tool to simulate and evaluate differential expression from bulk and especially single-cell RNA-seq data making it suitable for a priori and posterior power analyses. Availability and implementation The R package and associated tutorial are freely available at https://github.com/bvieth/powsimR. Contact [email protected] or [email protected]. Supplementary information Supplementary data are available at Bioinformatics online.

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عنوان ژورنال:
  • Bioinformatics

دوره 33 21  شماره 

صفحات  -

تاریخ انتشار 2017